Lignans and related compounds
Selleck Chemical LLC Etoposide S1225-10g
Etoposide is a semisynthetic derivative of podophyllotoxin which inhibits DNA synthesis via topoisomerase II inhibition activity which enhances double-strand and single-strand cleavage of DNA and reversibly inhibits repair by topoisomerase II binding Etoposide induces autophagy mitophagy and apoptosis
AdipoGen Podophyllotoxin
Chemical. CAS 518-28-5. Formula C22H22O8. MW 414.4. Isolated from Podophyllum emodi rhizomes. Potent microtubule assembly inhibitor. Anticancer compound. Cell death inducer. DNA topoisomerase II inhibitor. Cell cycle inhibitor at the metaphase. Antiviral and antihelminthic.
Medchemexpress LLC O-demethyl lenvatinib hydrochloride | 97.1% | 449.29 g/mol | C20H18Cl2N4O4 | 5 MG
O-demethyl lenvatinib hydrochloride is the O-demethylated metabolite of the kinase inhibitor lenvatinib, provided as a hydrochloride salt for research and analytical applications. It is intended as an analytical standard for in vitro studies, method development, and metabolite identification.
- Metabolite of lenvatinib for metabolite profiling and analytical reference.
- Hydrochloride salt form for improved stability and handling.
- High purity (97.1%) suitable for analytical workflows.
- Small 5 mg pack size ideal for method development and reference use.
- Molecular weight 449.29 g/mol and formula C20H18Cl2N4O4 for accurate calculations.
Medchemexpress LLC N-desmethyl promethazine hydrochloride | 60113-77-1 | MFCD18379322 | 5mg
N-demethyl Promethazine hydrochloride is a metabolite of Phenothiazine (HY-Y0055) Phenothiazine is an antibiotic which has insecticidal fungicidal antibacterial and anthelmintic activities
TARGETMOL CHEMICALS INC PICROPODOPHYLLOTOXIN 25MG
Also available in 1 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum) and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential antineoplastic activity. Picropodophyllotoxin (AXL 1717) specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with activities of other growth factor receptors such as receptors for insulin epidermal growth factor platelet-derived growth factor fibroblast growth factor and mast/stem cell growth factor (KIT). This agent shows potent activity in the suppression o f tumor cell proliferation and the induction of tumor cell apoptosis. IGF1R a receptor tyrosine kinase overexpressed in a variety of human cancers plays a critical role in the growth and survival of many types of cancer cells. purity: 99%